Punchline I: the nucleosome impedes cytosine methytlation

Punchline II: DDM1 allows cytosine methyltransferases (all of them) to get at the nucleosome-bound DNA

Punchline I: the nucleosome impedes cytosine methytlation

Punchline II: DDM1 allows cytosine methyltransferases (all of them) to get at the nucleosome-bound DNA