Punchline I: the nucleosome impedes cytosine methytlation
![](https://i0.wp.com/www.biolyons.org/wp-content/uploads/2018/10/DOxWHA2XUAAJADk.jpg?resize=764%2C264)
Punchline II: DDM1 allows cytosine methyltransferases (all of them) to get at the nucleosome-bound DNA
Punchline I: the nucleosome impedes cytosine methytlation
Punchline II: DDM1 allows cytosine methyltransferases (all of them) to get at the nucleosome-bound DNA